Walton Lundberg

KEY FINDINGS Ketamine induced positive, negative and cognitive schizophrenia symptoms together with neurotransmitters’ imbalance. In addition, ketamine treatment caused significant glutathione depletion, lipid peroxidation and reduction in catalase activity. Naringin and/or clozapine treatment significantly attenuated ketamine-induced…[Read more]

Also, the serum uric acid level in the AGE group was not significantly different at the follow-up time points, when compared with placebo. The mean changes of secondary endpoints from baseline to each time point did not show significant differences within and between the two groups. There were no adverse events reported by subjects or changes in…[Read more]

Mia40 regulates this competition as it has a rate-limiting role in mitochondrial protein import. Therefore, Mia40 is a dynamic regulator in mitochondrial biogenesis that can be exploited to stabilize cytosolic proteostasis.Retraction “Protective effects of microRNA-330 on amyloid β-protein production, oxidative stress, and mitochondrial…[Read more]

The geographical distribution of the mutants revealed interesting differences in the localization of aggregation-prone mutants of each protein. Aggregation-prone mutants of ORF7b were found in 7 European countries, whereas those of ORF3a in only 2. Aggregation-prone sequences of ORF7b, but not of ORF3a, were identified in Australia, India, Nepal,…[Read more]

The scanning electron microscopy (SEM) observations and energy dispersive spectroscopy (EDS) analysis also demonstrated the encapsulation patterns of target contaminants by forming hard microstructures of calcium silicate hydrate, ettringite and calcium-arsenic compounds. The outcomes of the study showed the potentiality of recycling the…[Read more]

© 2020 The Author(s).The data have been obtained for a series of substituted pteridinones and pyrimidines that were developed based on BI-D1870 to establish a structure-activity relationship for RSK inhibition. The 19 compounds, 12 of these with R- and S-isomeric forms, were docked into the ATP-binding site of the N-terminal domain of the RSK2…[Read more]

777 and 0.807 for recurrence and 0.767 and 0.776 for death, respectively. These were similar to those of the Arch system (0.763 and 0.796 for recurrence, 0.743 and 0.755 for death) and the Sica’s system (0.786 and 0.814 for recurrence, 0.762 and 0.773 for death).

We reported that the IASLC system for invasive lung ADC has prognostic…[Read more]

To observe the influence of regulating menstruation and promoting pregnancy acupuncture therapy on negative emotions in patients with premature ovarian insufficiency (POI).

A total of 60 patients with POI were randomly divided into an acupuncture group and a western medication group, 30 cases in each group. The acupuncture group was…[Read more]

However, the compliance rate was low. Adherence to metformin XR was 52% (IQR42% to 61%) based on the remaining tablets in the container after 4months of intervention. None of the reported side effects were deemed to be related to the study treatment and no significant differences were observed between the metformin XR and the control…[Read more]