Boysen Hegelund

Furthermore, KLF16 expression was correlated with MYC signaling activity. Conclusion KLF16 was overexpressed in PCa tissues compared to normal tissues. KLF16 knockdown suppressed PCa cell growth in vitro and in vivo, and a deficiency of KLF16 inhibited activation of MYC signaling. © 2020 Zhang et al.Background Acute myeloid leukemia (AML) is a…[Read more]

The spectrum of soft-tissue mass is varied, including neoplastic and nonneoplastic/inflammatory lesions. However, soft-tissue tumors have similar imaging findings and, therefore, the diagnosis of soft-tissue mass is challenging. Although careful assessment of the internal characteristics on imaging can often narrow the differential diagnoses, the…[Read more]

her parallel trials of the DAWN consortium will amplify the chance of identifying successful treatment strategies and allow comparison of treatment effects within an identical clinical context.

EU Clinical trials register EudraCT Nb 2020-001614-38 . Registered on 22 April 2020.

EU Clinical trials register EudraCT Nb 2020-001614-38 .…[Read more]

Vasomotor dysfunction is one of the key pathological aspects of shock and heart failure (HF). Shenfu injection (SFI) has been widely used for the treatment of shock and HF in China. Pharmacological studies have suggested that SFI can reduce peripheral circulation resistance and improve microcirculation. However, whether it has a regulatory effect…[Read more]

To evaluate the efficacy and safety of transition from premixed and intensive insulin to twice-daily insulin degludec/aspart (IDegAsp) co-formulation in patients with type 2 diabetes mellitus.

In this 12-week study, patients receiving twice-daily premixed insulin therapy in group 1 (

= 55) were switched to twice-daily IDegAsp. In group…[Read more]

These contours were checked for quality and edited if necessary to ensure adherence to RTOG 1106 contouring guidelines. DATA FORMAT AND USAGE NOTES The CT images and RTSTRUCT files are available in DICOM format. The regions of interest were named according to the nomenclature recommended by AAPM Task Group 263 as Lung_L, Lung_R, Esophagus, Heart,…[Read more]

ions Assessment, Development, and Evaluation (GRADE) approach. See online Appendix A (Tables A1 for definitions and A2 for interpretations of strong and weak recommendations).

Gynaecologists, urologists, urogynaecologists, and other health care providers who assess, counsel, and care for women with POP.

All statements refer to…[Read more]