Klavsen Snider

The use of the appendix is a safe and feasible option for ureteral reconstruction in appropriately selected adult patients when primary ureteral repair is not possible.

The use of the appendix is a safe and feasible option for ureteral reconstruction in appropriately selected adult patients when primary ureteral repair is not possible.

To…[Read more]

The aim of this study was to investigate whether treatment with rapamycin plus vildagliptin restores β-cell function in patients with long-standing type 1 diabetes.

A phase 2, single-center, randomized, double-blind, placebo-controlled study was conducted in long-standing type 1 diabetes patients randomly assigned (111) to 4 weeks of…[Read more]

Widespread structural brain abnormalities have been consistently reported in schizophrenia, but their relation to the heterogeneous clinical manifestations remains unknown. In particular, it is unclear whether anatomical abnormalities in discrete regions give rise to discrete symptoms or whether distributed abnormalities give rise to the broad…[Read more]

Karyotyping of long-term cultured chorionic villus sample may give rise to false negative results due to placental mosaicism. To ensure accurate prenatal diagnosis, discordance between karyotyping of chorionic villi cells, fetal ultrasound and NIPT result should be verified by amniocentesis or cordocentesis and application of multiple cytogenetic…[Read more]

Layer 2/3 pyramidal neurons (L2/3 PyNs) of the cortex extend their basal dendrites near the soma and as apical dendritic tufts in layer 1, which mainly receive feedforward and feedback inputs, respectively. It is suggested that neuromodulators such as serotonin and acetylcholine may regulate the information flow between brain structures depending…[Read more]

248 W*m-1*K-1 for 2.5 wt% addition of PANI. The key factor is that the stability of the sample is improved for MoS2/ PANI nanocomposites than pristine MoS2. Our work paved a new approach to improve TE performance by preparing TE MoS2 material through simple chemical route.This work presents solution- and solid-state evidence of the enhancement of…[Read more]

PAK inhibitor abolishes Akt phosphorylation, inhibits platelet aggregation in vitro and arterial thrombus formation in vivo. We propose that the PAK-PI3K/Akt pathway mediates platelet aggregation downstream of Gi and G12/13, and PAK may represent a potential antiplatelet and antithrombotic target.After total laryngectomy, regaining ability to…[Read more]

am intervention for refractory AP patients, the lack of internal validity of the studies undermines the partially positive results.

The significance of the distal tip extension mechanism (DTEM) arises when the insertion tube of the colonoscope is no longer able to move further inside the colon, and when a longer insertion tube is needed. The…[Read more]

Activation of NF-κB transcription factors is critical for innate immune cells to induce inflammation and fight against microbial pathogens. On ARS-853 clinical trial , the excessive and prolonged activation of NF-κB causes massive inflammatory damage to the host, suggesting that regulatory mechanisms to promptly terminate NF-κB activation are im…[Read more]

The last two factors are ‘laws and regulations’ and ‘waste bin arrangement’. By understanding the influence of various factors on residents’ satisfaction, this study aims to help in designing an effective waste management system to reduce the cost of MHSW management, and to raise the residents’ satisfaction with municipal solid waste treatment.…[Read more]