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BACKGROUND To evaluate and analyze the therapeutic effect of stereotactic soft channel puncture and drainage on hypertensive cerebral hemorrhage. METHODS Sixty patients with hypertensive cerebral hemorrhage admitted to our hospital from September 2014 to September 2019 were selected for study and randomly divided into study group (n=30) and routine group (n=30) according to admission number. Two groups of patients were given basic treatment after admission, while routine group patients were given small bone window hematoma removal, study group patients were given stereotactic soft channel puncture and drainage, and the clinical effects of the two groups were analyzed. PD98059 RESULTS The total effective rate of the study group was 96.67%, which was significantly higher than that of the routine group (80.00%), and the difference was statistically significant (P0.05). After treatment, the CD8+ positive cell rate in the study group was lower than that in the conventional group, and the CD3+ positive cell rate was higher than that in the conventional group, with statistically significant difference (P less then 0.05). The incidence of postoperative complications such as pulmonary infection, urinary tract infection, liver and kidney dysfunction in the study group was lower than that in the conventional group, and the difference was statistically significant (P less then 0.05). CONCLUSIONS Stereotactic soft-channel puncture and drainage has the advantages of less trauma, less bleeding, fewer complications and rapid postoperative recovery. It can be used for the treatment of hypertensive cerebral hemorrhage, promote the recovery of neurological function of patients, improve independent living standard and effectively improve prognosis.BACKGROUND To investigate the imaging findings of bladder paraganglioma (BPG) and improve the imaging recognition and diagnostic accuracy of the disease. METHODS The clinical and imaging data of 10 cases of BPG confirmed by operation and pathology were retrospectively analyzed from the aspects of tumor location, size and morphology, presence or absence of necrosis, cystic change and calcification, and enhancement methods. RESULTS Of the 10 cases, 7 cases underwent basal and contrast enhanced computed tomography (CT) scan examination, 1 case underwent basal and contrast enhanced MRI scan examination, and 9 cases underwent ultrasonography examination; 5 cases were located in the right wall of bladder, 3 cases were located in the left wall, and 2 cases were located in the bottom wall; 2 cases showed necrosis, 1 case had cystic degeneration, and 2 cases had arcuate and semicircular calcification; both contrast enhanced CT and MRI examinations showed significant post-contrast enhancement; in 9 cases of ultrasonography examination, 5 cases had hypoechoic mass, 3 cases had moderate echoic mass, and 1 case had hyperechoic mass. CONCLUSIONS The imaging findings of BPG have certain characteristics, and combining with clinical history is helpful for accurate preoperative diagnosis.Advanced intrahepatic cholangiocarcinoma (ICC) is a highly challenging malignancy characterized by rapid progression and poor prognosis. Although programmed cell death-1/programmed cell death1 ligand-1 (PD-1/PD-L1) inhibitors licensed abroad have achieved certain effectiveness in treating various tumors, few studies have investigated the efficacies of these drugs on advanced ICC. Here, we describe a 63-year-old female patient with stage IV ICC involving the porta hepatis, retroperitoneal lymph nodes, and left adrenal gland, along with right femur metastasis. She suffered from lower back pain that had affected her sleep. A pathological fracture of her right femur was detected. Multiple lymph node metastases were found in the left adrenal glands, porta hepatis, and retroperitoneum. She failed the first- and secondline chemotherapies. After 6 cycles of combined therapy with sintilimab injection (PD-1) and tegafurgimeracil-oteracil potassium capsules (S-1), the patient’s condition gradually improved and finally achieved partial remission (PR). The patient’s pain score decreased, and her quality of life was significantly improved. The third-line treatment was efficacious and significantly improved survival. We can therefore speculate that PD-1 plays an important role in the treatment of advanced ICC and can benefit patients with similar conditions.Recently high-frequency electric knife and abdominal binder are widely used in the abdominal operation in China. Nevertheless, with the high occurrence of the abdominal wound, we think that whether both these operations could be used or not. Here, we report the case of a 40-year-old female patient where negative pressure wound therapy (NPWT) was applied to her dehisced abdominal wound as well as fat liquefaction and large skin necrosis with pleasing results. The patient with high fever was referred to our department from her earlier hospital for 6 days after cesarean delivery. During the surgery, her earlier doctor used a high-frequency electric knife for convenient-using, and after the operation, the patient immediately used an abdominal binder for good shape. However, the abdominal surgical incision was opened at postoperative day 3, with fat liquefaction releasing large fatty acids along both abdominal sides with penetration under the abdominal binder. After admitted at postoperative day 6 with aggravating wound, surgery was considered because of no reduction in the size of the wound. A series of vacuum sealing drainage (VSD) or vacuum-assisted closure (VAC) as well as others, were operated. In the admitted 25th day, the wound was completely closed. NPWT is a practical and effective therapy for the treatment of numerous refractory and intractable wounds. Therefore, we suggest that the high-frequency electric knife and an abdominal binder should be avoided using an abdominal operation. This case is the first report of the use of NPWT over a dehisced abdominal wound with fat liquefaction and large skin necrosis on a postpartum patient in China.BACKGROUND To establish a dietary self-management evaluation indicators scale for kidney transplant recipients and to test the reliability and validity of the scale. METHODS Based on the knowledge attitude practice model (KAP model) of health-related behavior changes, an evaluation indicators scale of dietary self-management ability of kidney transplant recipients was constructed through a literature review, expert consultation and group discussion. A questionnaire survey was carried out with 102 kidney transplant recipients from a large tertiary hospital to test the reliability and validity of the constructed scale. RESULTS The dietary self-management ability scale for kidney transplant recipients had 29 items in 3 dimensions. The content validity at the scale level was 0.969, and the content validity at the item level was 0.778-1.000. Exploratory factor analysis extracted 3 common factors, and the cumulative variance contribution rate was 68.610%; the correlation coefficient between each dimension was 0.467-0.